化工社化工社 化学情報印刷レポート · 研究参考用
1-Propylboronic acid → Ethyl 3-methyl-6-propylpyrazine-2-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Propylboronic acid | HCID 351065 | — |
| 反応物 | Ethyl 6-chloro-3-methylpyrazine-2-carboxylate | HCID 87384166 | — |
| 生成物 | Ethyl 3-methyl-6-propylpyrazine-2-carboxylate | HCID 67397137 | — |
反応手順
The preparation was performed in a similar manner as Reference Example 1.13 (d) from ethyl 6-chloro-3-methylpyrazine-2-carboxylate (Reference Example 1.13 (c)) (1.50 g, 7.48 mmol) and n-propylboronic acid (1.32 g, 15.0 mmol) to give ethyl 3-methyl-6-propylpyrazine-2-carboxylate. MS (APCI): m/z 209 (M+H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08969376B2 |
| 出典データセット | uspto-grants-2015_03 |
| ORD ID | ord-b64fd4d29759401892e2e8e56af408a3 |
| 出典メモ | uspto-grants-2015_03 |