化工社化工社 化学情報印刷レポート · 研究参考用
Potassium Carbonate → HCID 66808423、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 4-Chloro-3-nitrophenol | HCID 69127 | — |
| 反応物 | 1-Bromo-4-(1-bromoethyl)benzene | HCID 9838146 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | HCID 66808423 | HCID 66808423 | 92.2% |
反応手順
The product from Example 44A (995 mg, 3.77 mmol) was reacted with 4-chloro-3-nitro-phenol (650 mg, 3.77 mmol) in 15 mL of DMF with K2CO3 (10.4 g, 3.77 mmol) at 80° C. for 3 h. Cooled to room temperature and diluted with water. Extracted with CH2Cl2, washed four times with water. Dried over Na2SO4, filtered and concentrated under vacuum giving the title compound (1.24 g, 92%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08236950B2 |
| 出典データセット | uspto-grants-2012_08 |
| ORD ID | ord-01ea14048f1e47a8be43e546416167ed |
| 出典メモ | uspto-grants-2012_08 |