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Beta-Alanine → 2-[(6-nitro-2H-1,3-benzodioxol-5-yl)methylidene]propanedinitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Beta-Alanine | HCID 239 | — |
| 反応物 | Water | HCID 962 | — |
| 反応物 | Malononitrile | HCID 8010 | — |
| 反応物 | 6-Nitro-1,3-benzodioxole-5-carboxaldehyde | HCID 12840 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 2-[(6-nitro-2H-1,3-benzodioxol-5-yl)methylidene]propanedinitrile | HCID 707914 | 80.6% |
反応手順
1 g (5.1 mmol) 3,4-Methylenedioxy-6-nitrobenzaldehyde, 0.4 g (6 mmol) malononitrile and 0.2 g β-alanine in 30 ml ethanol were stirred 16 hours at room temperature, 50 ml H2O was added and the reaction mixture was filtered, giving 1 g (80% yield) of a bright yellow solid, m.p. 104° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | USRE038761E1 |
| 出典データセット | uspto-grants-2005_07 |
| ORD ID | ord-a91411fcbc114066b6c3c11805a2e5e1 |
| 出典メモ | uspto-grants-2005_07 |