化工社化工社 化学情報印刷レポート · 研究参考用
1-{5-[4-(Trifluoromethyl)phenyl]thien-3-yl}ethanol → 1-{3-Methyl-5-[4-(trifluoromethyl)phenyl]thien-2-yl}ethanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-{5-[4-(Trifluoromethyl)phenyl]thien-3-yl}ethanol | HCID 21986431 | — |
| 反応物 | 3-Methyl-5-[4-(trifluoromethyl)phenyl]thiophene-2-carbaldehyde | HCID 21986550 | — |
| 反応物 | HCID 178418573 | HCID 178418573 | — |
| 生成物 | 1-{3-Methyl-5-[4-(trifluoromethyl)phenyl]thien-2-yl}ethanol | HCID 21986359 | — |
反応手順
The title compound was prepared using a method analogous to that used for the preparation of 1-{5-[4-(trifluoromethyl)phenyl]thien-3-yl}ethanol (intermediate 126) using 3-methyl-5-[4-(trifluoromethyl)phenyl]thiophene-2-carbaldehyde (intermediate 74) and methyl magnesium bromide.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07091237B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-11e7000f7bdf4162a75e44daa17cdd60 |
| 出典メモ | uspto-grants-2006_08 |