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HRID 9685作成日：2026年10月24日

Methyl 3-(bromomethyl)-5-[4-(trifluoromethyl)phenyl]thiophene-2-carboxylate → {3-{[(2-Isopropyl-6-methylpyrimidin-4-yl)oxy]methyl}-5-[4-(trifluoromethyl)phenyl]thien-2-yl}methanol

https://huagongshe.com/ja/reaction/9685

反応式

関与物質

役割名称HCID仕込み量
反応物Methyl 3-(bromomethyl)-5-[4-(trifluoromethyl)phenyl]thiophene-2-carboxylateHCID 21986302—
反応物HCID 178419104HCID 178419104—
生成物{3-{[(2-Isopropyl-6-methylpyrimidin-4-yl)oxy]methyl}-5-[4-(trifluoromethyl)phenyl]thien-2-yl}methanolHCID 21986496—

反応手順

The title compound was prepared using methyl 3-(bromomethyl)-5-[4-(trifluoromethyl)phenyl]thiophene-2-carboxylate (intermediate 132) and 2-isopropyl-6-methyl-4-pyrimidinol.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07091237B2
出典データセットuspto-grants-2006_08
ORD IDord-af55f1b94a2548bbb8c81307374898be
出典メモuspto-grants-2006_08