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{5-[2,5-Difluoro-4-(trifluoromethyl)phenyl]-3-methylthien-2-yl)methanol → Ethyl[4-({5-[2,5-difluoro-4-(trifluoromethyl)phenyl]-3-methylthien-2-yl}methoxy)-2-methylphenoxy]acetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | {5-[2,5-Difluoro-4-(trifluoromethyl)phenyl]-3-methylthien-2-yl)methanol | HCID 21986329 | — |
| 反応物 | Ethyl (4-hydroxy-2-methylphenoxy)acetate | HCID 21986458 | — |
| 反応物 | Ethyl{2-methyl-4-[({5-[4-(trifluoromethyl)phenyl]-3-furyl}methyl)thio]phenoxy}acetate | HCID 21986477 | — |
| 生成物 | Ethyl[4-({5-[2,5-difluoro-4-(trifluoromethyl)phenyl]-3-methylthien-2-yl}methoxy)-2-methylphenoxy]acetate | HCID 21986311 | — |
反応手順
The title compound was prepared by a method analogous to that used for the preparation of ethyl{2-methyl-4-[({5-[4-(trifluoromethyl)phenyl]-3-furyl}methyl)thio]phenoxy}acetate (example 1) using ethyl(4-hydroxy-2-methylphenoxy)acetate (intermediate 7) and {5-[2,5-difluoro-4-(trifluoromethyl)phenyl]-3-methylthien-2-yl}methanol (intermediate 120).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07091237B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-ab08d73f10fa4a0ea110a92bbee126a5 |
| 出典メモ | uspto-grants-2006_08 |