化工社化工社 化学情報印刷レポート · 研究参考用
Water → HCID 178507362、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Lithium aluminum hydride | HCID 28112 | — |
| 反応物 | 5-nitro-1H-indazole-3-carboxylic Acid | HCID 7144652 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | HCID 178507362 | HCID 178507362 | 19.9% |
反応手順
5-nitro-1H-indazole-3-carboxylic acid (500 mg, 0.002 mol) was dissolved in 50 mL THF, added lithium tetrahydroaluminate (366 mg, 0.00964 mol) in 3 portions and stirred at room temperature overnight. 65 mg (15%). Water (366 μL), 15% NaOH solution (366 μL), and water (1.1 mL) were added cautiously and the mixtured was filtered. The filtrate was concentrated under vacuum to give the product (65 mg, 15%) as an oil. m/z=160.0.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07312233B2 |
| 出典データセット | uspto-grants-2007_12 |
| ORD ID | ord-620f4c73f84141379fb79a07e6e77db7 |
| 出典メモ | uspto-grants-2007_12 |