関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Dimethyl Sulfate | HCID 6497 | — |
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 反応物 | 3,6-Dichlorosalicylic acid | HCID 18844 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | Dicamba | HCID 3030 | — |
反応手順
2-Hydroxy-3,6-dichlorobenzoic acid (44.4 g) is dissolved in a solution of potassium hydroxide (11.2 g, 0.2 mole) and water (100 ml). The solution is heated to reflux (about 100° C.) and stirred vigorously while dimethyl sulfate (63.1 g, 0.5 mole) is added dropwise. The reaction mixture is then treated with a solution of potassium hydroxide (14.0 g, 0.25 mole) in 25.0 ml of water and refluxed for an additional 2 hours. The reaction mixture is then cooled and acidified to Congo red with hydrochloric acid to precipitate the desired 2-methoxy-3,6-dichlorobenzoic acid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04161611 |
|---|
| 出典データセット | uspto-grants-1979_07 |
|---|
| ORD ID | ord-c60020878259412b8573d192325b9d4d |
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| 出典メモ | uspto-grants-1979_07 |
|---|
