Phloroglucinol → 2,4-Dimethyl-1,3,5-benzenetriol

HRID 980312

反応式

HRID 980312 の反応式
[C:1]1([CH:9]=[C:7]([OH:8])[CH:6]=[C:4]([OH:5])[CH:3]=1)O.CN(C)[CH:12]=[O:13].P(Cl)(Cl)(Cl)=O.O1CCOC[CH2:21]1>>[OH:8][C:7]1[C:6]([CH3:21])=[C:4]([OH:5])[CH:3]=[C:12]([OH:13])[C:9]=1[CH3:1]

参加物

5

反応物 4

HCID 359PhloroglucinolHCID 6228DimethylformamideHCID 24813Phosphorus oxychlorideHCID 312751,4-Dioxane

生成物 1

HCID 782142,4-Dimethyl-1,3,5-benzenetriol

反応条件

温度
40 °C

実験手順

0.6 kg of phloroglucinol is dissolved in 1.4 liters of dioxan and a mixture containing 0.8 liters of N,N-dimethylformamide and 0.96 liters of phosphorus oxychloride is added slowly and with vigorous stirring. The addition of the reagent having been completed, the reaction is maintained at 40° C. for 12 hours containing the stirring and then the whole is poured over 10 kg of crushed ice.

後処理

  1. additionis added slowly and with vigorous stirring
  2. additionThe addition of the reagent
  3. additioncontaining the stirring and then the whole

出典と根拠

ORDレコード
ord-95c952b9479f46159281fca5ca64d23e
出典データセット
uspto-grants-1987_01
特許番号
US04636569

関連ノート

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