Cobalt oxide (Co2O3)

HCID 10176285CAS 1308-04-9

기본 정보

표준 SMILES: [Co+3].[Co+3].[O-2].[O-2].[O-2]
InChIKey: KAGOZRSGIYZEKW-UHFFFAOYSA-N
분자식: Co2O3
평균 분자량: 165.865 g/mol
단동위원소 질량: 165.85113386

개요

Cobalt(III) oxide is an inorganic compound with the formula Co2O3 and is an oxide of cobalt. It is used as a catalyst. Cobalt is a metallic element with the atomic number 27. It is found naturally in rocks, soil, water, plants, and animals. In small amounts cobalt is an essential element for life, as it is part of vitamin B12. However, excess exposure is known to exhibit toxic effects. (L29, L30, L493)

이름 및 식별자

우선 이름: Cobalt oxide (Co2O3)
IUPAC: bis(cobalt(3+));tris(oxygen(2-))

이름 및 동의어

Cobalt oxide (Co2O3)1308-04-9DTXSID20893870RefChem:577892DTXCID601323908C.I. 77323COBALT(III) OXIDE BLACKcobalt(3+);oxygen(2-)oxo(oxocobaltiooxy)cobaltSCHEMBL116878Cobalt(3+) oxide (2/3)

데이터베이스 식별자

CAS: 1308-04-9
PubChem CID: 10176285
DTXSID: DTXSID20893870

물성

구조 계산 물성

극성 표면적: 3 Å²
수소 결합 공여자 수: 0
수소 결합 수용자 수: 3
회전 가능 결합 수: 0
무거운 원자 수: 5
형식 전하: 0
복잡도: 0

실험 및 물리화학적 성질

Density5.2 g/cm³

SolubilitySolubility in water: none

Decomposition895 °C

Physical DescriptionBLACK-GREY CRYSTALLINE POWDER.

안전 및 규제

유해성 정보

Regulatory InformationChemical: Cobalt oxide (Co2O3)

Other Safety InformationIMAP assessments - Cobalt (III) oxides: Human health tier II assessment

Fire HazardsNot combustible.

Chemical DangersReacts violently with hydrogen peroxide. Reacts with reducing agents.

안전 및 보호

Fire FightingIn case of fire in the surroundings, use appropriate extinguishing media.

First Aid Measures · 4건

Fresh air, rest. Refer for medical attention.

Remove contaminated clothes. Rinse and then wash skin with water and soap.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Refer for medical attention .

Safe StorageSeparated from reducing agents and hydrogen peroxide.

Spillage Disposal · 1건

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

Eye PreventionWear safety goggles or eye protection in combination with breathing protection.

Inhalation RiskA harmful concentration of airborne particles can be reached quickly when dispersed.

독성 정보

TreatmentTreatment of cobalt poisoning is symptomatic. (L29)

Health EffectsExposure to high amount of cobalt can cause heart, lung, kidney, and liver damage. Skin contact is known to result in contact dermatitis. Cobalt may also have mutagenic and carcinogenic effects. (L29, L30)

Exposure Routes · 2건

The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

Inhalation (L29) ; oral (L29) ; dermal (L29)

Toxicity Summary · 1건

Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, causing increased lipid peroxidation, DNA damage, and inducing certain enzymes that lead to cell apoptosis. Cobalt has also been shown to block inorganic calcium channels, possibly impairing neurotransmission. Cobalt can also chelate lipoic acids, impairing oxidation of pyruvate or fatty acids. In addition, cobalt may inhibit DNA repair by interacting with zinc finger DNA repair proteins, and has also been shown to inhibit heme synthesis and glucose metabolism. Cobalt may activate specific helper T-lymphocyte cells and interact directly with immunologic proteins, such as antibodies (IgA and IgE) or Fc receptors, resulting in immunosensitization. (L29)

Signs and Symptoms · 4건

Cough. Sore throat. Shortness of breath. Wheezing.

Redness. Pain.

Abdominal pain. Nausea.

Cobalt inhalation can cause asthma-like breathing problems. Skin contact is known to result in contact dermatitis, which is characterized by irritation and rashes. Ingesting large amounts of cobalt may cause nausea and vomiting. (L2090)

Carcinogen Classification2B, possibly carcinogenic to humans. (L135)

화학 및 산업

약리 정보

Metabolism/Metabolites · 1건

Cobalt is absorbed though the lungs, gastrointestinal tract, and skin. Since it is a component of the vitamin B12 (cyanocobalamin), it is distributed to most tissues of the body. It is transported in the blood, often bound to albumin, with the highest levels being found in the liver and kidney. Cobalt is excreted mainly in the urine and faeces. (L29)

용도 및 제조

UsesCobalt(III) oxide is used as a catalyst. (L493)

General Manufacturing InformationCobalt oxide (Co2O3): ACTIVE

연결된 노트

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