(Z)-Flunarizine

HCID 1711971CAS 693765-11-6

기본 정보

표준 SMILES: Fc1ccc(C(c2ccc(F)cc2)N2CCN(C/C=C\c3ccccc3)CC2)cc1
InChIKey: SMANXXCATUTDDT-DAXSKMNVSA-N
분자식: C26H26F2N2
평균 분자량: 404.5 g/mol

이름 및 식별자

우선 이름: (Z)-Flunarizine
IUPAC: 1-[bis(4-fluorophenyl)methyl]-4-[(Z)-3-phenylprop-2-enyl]piperazine
영어명: Flunarizine EP Impurity D
분자식: C26H26F2N2
분자량: 404.49

이름 및 동의어

693765-11-6FLUNARIZINE IMPURITY DFlunarizine EP Impurity D(Z)-Flunarizine1-[Bis(4-fluorophenyl)methyl]-4-[(Z)-3-phenyl-2-propenyl]piperazine1-[bis(4-fluorophenyl)methyl]-4-[(Z)-3-phenylprop-2-enyl]piperazine(Z)-1-(bis(4-fluorophenyl)methyl)-4-(3-phenylallyl)piperazinePiperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2Z)-3-phenyl-2-propen-1-yl]-; Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2Z)-3-phenyl-2-propenyl]- (9CI); 1-[Bis(4-fluorophenyl)methyl]-4-[(2Z)-3-phenyl-2-propen-1-yl]piperazine; 1-[Bis(4-fluorophenyl)methyl]-4-[(2Z)-3-phenylprop-2-enyl]piperazine; (Z)-FlunarizineFlunarizine, (Z)-Tocris-0522Lopac-F-8257FLUNARIZINEIMPURITYD

이름 더 보기

(Z)Sudan IFlunarizine Imp.DFlunarizine hydrochloride DFlunarizine EP Impurity D DiHClFlunarizine EP Impurity D(Hydrochloride)Flunarizine EP Impurity D（(Z)-Flunarizine）Flunarizine Impurity 4（Flunarizine EP Impurity D）(Z)-1-[bis(4-fluorophenyl)methyl]-4-(cinnamyl)piperazine

Z6Z4W9HSH3orb3181097CHEMBL1319373SCHEMBL16225927NCGC00015449-01NCGC00015449-02NCGC00018102-01NCGC00018102-02

데이터베이스 식별자

CAS: 693765-11-6
PubChem CID: 1711971
ChEMBL: CHEMBL1319373
UNII: Z6Z4W9HSH3
Nikkaji: J292.397A

물성

구조 계산 물성

XLogP: 6
극성 표면적: 6.5 Å²
수소 결합 공여자 수: 0
수소 결합 수용자 수: 4
회전 가능 결합 수: 6
무거운 원자 수: 30
형식 전하: 0
복잡도: 487

물리화학적 성질

끓는 점: 511.3 · 511.3±50.0 °C(Predicted)
밀도: 1.17 · 1.170±0.06 g/cm3(Predicted)
용해도: 클로로포름(약간 용해됨), DMSO(약간 용해됨), 메탄올(약간 용해됨)
산도 계수 (pKa): 6.99 · 6.99±0.10(Predicted)
물리적 상태: 두꺼운 기름
색상: 무색~황색

화학 및 산업

응용 분야

용도(Z)-Flunarizine is Z-isomer of Flunarizine(F455200, Dihydrochloride), which is a calcium channel blocker. Flunarizine is a fluorinated derivative of Cinnarizine and a vasodilator (cerebral and peripheral). EP Impurity C

상·하류 제품 정보

상류 원료

Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-(2,2-dimethoxyethyl)-1-Piperazineacetaldehyde, 4-[bis(4-fluorophenyl)methyl]-Flunarizine 페닐마그네슘클로라드 벤질트리페닐포스포늄 클로라이드

공급사38 곳

济南百隆化学有限公司[email protected] · [email protected]

艾吉析科技（上海）有限公司17717235263 · [email protected]

怀化元研达生物技术有限责任公司18711085600 · [email protected]

合肥翰刚医药科技有限公司+8618062405514 · [email protected]

广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]

연결된 노트

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