Menadione Sodium Bisulfite (HCID 23665888)

이름 및 식별자

우선 이름: Menadione Sodium Bisulfite
IUPAC: sodium 2-methyl-1,4-dioxo-3H-naphthalene-2-sulfonate
현지명: 메나디온중아황산나트륨
영어명: Menadione sodium bisulfite
분자식: C11H11NaO5S
분자량: 277.25

이름 및 동의어

Menadione sodium bisulfiteKavitaminSodium menadione bisulfiteVikasolumMSBCVitamin K3 sodium bisulfiteNatrium menadionsulfonicumMenadione sodium bisulfite anhydrousKlotogenMenaphthone sodium bisulfiteMenaphthone sodium bisulphiteMenadioni natrii hydrogensulfis

이름 더 보기

메나디온중아황산나트륨MSBMenadione Sodium BisulfateVitamin K3 MSBMenadione Sodium BisulphateMNB,MSNVITAMIN K3 MSB96Menadion sodium bisulfiteMENADIONESODIUMBISULPHITEMenadione bisulfite (sodium)

Menadioni natrii bisulfisMenachinonum natrium bisulfurosumMenadione sodium hydrogen sulfiteBisulfito sodico de menadionaBisulfite sodique de menadioneDTXSID0040547Menadione sodio bisolfito2-Methylnaphthoquinone sodium hydrogen sulfite

데이터베이스 식별자

CAS: 130-37-0、57414-02-5
PubChem CID: 23665888
DTXSID: DTXSID0040547
ChEMBL: CHEMBL2107211、CHEMBL2358118
ChEBI: CHEBI:63928
UNII: 97K34V88SA
EC Number: 204-987-0、611-523-4
Nikkaji: J5.433J

물성

구조 계산 물성

극성 표면적: 99.7 Å²
수소 결합 공여자 수: 0
수소 결합 수용자 수: 5
회전 가능 결합 수: 1
무거운 원자 수: 18
형식 전하: 0
복잡도: 466

물리화학적 성질

녹는점: 121 · 121-124°C
저장 조건: -20 °C · -20°C
용해도: 2 O: · H2O: ≥50mg/mL, 투명, 무색 ~ 희미한 노란색
물리적 상태: Solid
색상: White to off-white
생물학적 소스: synthetic (organic)
수용성: 50 mg/mL, · water: soluble 50mg/mL, clear, colorless to light yellow
InChI: InChI=1S/C11H10O5S.Na.H/c1-11(17(14,15)16)6-9(12)7-4-2-3-5-8(7)10(11)13;;/h2-5H,6H2,1H3,(H,14,15,16);;
InChIKey: JWNUEPMMANLFQO-UHFFFAOYSA-N
SMILES: O=C1C(CC(=O)C2=CC=CC=C12)(C)S(O)(=O)=O.[NaH]
EPA: Menadione sodium bisulfite (130-37-0)

화학적 성질

white powder

안전 및 규제

GHS 분류

GHS Classification · 6건

Warning

H315: Causes skin irritation [Warning Skin corrosion/irritation]；H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]；H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

P264, P264+P265, P273, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, P362+P364, P391, and P501 (click each P-code to see the statement)

Warning

유해성 정보

Regulatory Information · 3건

Chemical: 2-Naphthalenesulfonic acid, 1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-, sodium salt

Regulation (EC) No 1831/2003 (amended)

Menadione sodium bisulfite anhydrous: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazard Classes and Categories · 4건

Skin Irrit. 2 (99.6%)；Eye Irrit. 2 (100%)；Aquatic Acute 1 (99.6%)；Aquatic Chronic 1 (99.6%)

Skin Irrit. 2 (100%)；Eye Irrit. 2 (100%)；STOT SE 3 (100%)

Eye irritation - category 2；Skin irritation - category 2；Hazardous to the aquatic environment (acute) - category 1；Hazardous to the aquatic environment (chronic) - category 1

Skin Irrit. 2；Eye Irrit. 2；Aquatic Acute 1；Aquatic Chronic 1

규제 정보

Regulatory Information · 3건

Chemical: 2-Naphthalenesulfonic acid, 1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-, sodium salt

Regulation (EC) No 1831/2003 (amended)

Menadione sodium bisulfite anhydrous: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

안전 데이터

wgk: 3
tsca: TSCA listed
ridadr: UN 3077 9 / PGIII
risk_code: 36-50/53-36/38
hazard_code: Xi,N
safety_code: 26-61-60-24/25
Hazard Classifications: Aquatic Acute 1Aquatic Chronic 1Eye Irrit. 2Skin Irrit. 2
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

약리 정보

MeSH Pharmacological Classification · 2건

Agents that prevent fibrinolysis or lysis of a blood clot or thrombus. Several endogenous antiplasmins are known. The drugs are used to control massive hemorrhage and in other coagulation disorders.

Organic substances that are required in small amounts for maintenance and growth, but which cannot be manufactured by the human body.

용도 및 제조

General Manufacturing Information2-Naphthalenesulfonic acid, 1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-, sodium salt (1:1): ACTIVE

응용 분야 · 2건

개요Menadione sodium bisulfite (MSB, also known as vitamin K3), is a crucial growth regulator mediating plant defense response. This substance is used clinically in China to treat hemorrhagic diseases caused by vitamin K deficiency and globally as a vitamin K supplement. This compound and its complex (MSBC) are water-soluble compounds. Menadione and the menadione sodium bisulfite complex are the sources of vitamin K activity in commercial laboratory rodent diets. Menadione possesses high biological activity, but its absorption depends on the amount of fat in the diet. Compared with Menadione, the menadione sodium bisulfite complex is more readily absorbed and is almost as active on a molar basis as phylloquinone. XTT, a tetrazolium salt, could converted to formazan in the presence of an electron coupling reagent such as menadione sodium bisulfite. The formed formazan does not need to be solubilized. Hence, the XTT test, a cytotoxicity evaluation method, is quicker and safer compared with MTT[1-2].

용도Menadione sodium bisulfite has been used:as a priming agent in tomato for improving salt toleranceto induce reactive oxygen species (ROS) in human lung epithelium BEAS-2B microtissuesto induce endogenous superoxide production in mouse C17.2 neural stem cells

상·하류 제품 정보

상류 원료

공급사50 곳

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

Shandong chuangyingchemical Co., Ltd.18853181302 · [email protected]

湖南韵邦生物科技股份有限公司85561037 15386497078 · [email protected]

武汉欣扬瑞和化学科技有限公司153-07155313 15307155313 · [email protected]

湖北金梭生物科技有限公司00123456789 · [email protected]

추가 설명 · 1건

정의ChEBI: An organic sodium salt that is the monosodium salt of menadione sulfonate. A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation i vivo.

연결된 노트

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