(E)-2'-하이드록시칼콘

2'-Hydroxychalcone

HCID 638276CAS 1214-47-7
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기본 정보

표준 SMILES
O=C(/C=C/c1ccccc1)c1ccccc1O
InChIKey
AETKQQBRKSELEL-ZHACJKMWSA-N
분자식
C15H12O2
평균 분자량
224.25 g/mol
단동위원소 질량
224.08372962

개요

2'-hydroxychalcone is a member of the class of chalcones that is trans-chalcone substituted by a hydroxy group at position 2'. It has a role as an anti-inflammatory agent. It is a member of chalcones and a member of phenols. It is functionally related to a trans-chalcone.

이름 및 식별자

우선 이름
2'-Hydroxychalcone
IUPAC
(E)-1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one
현지명
(E)-2'-하이드록시칼콘
영어명
(E)-2'-hydroxychalcone
분자식
C15H12O2
분자량
224.25

이름 및 동의어

2'-Hydroxychalcone1214-47-7(E)-1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one1-(2-Hydroxyphenyl)-3-phenyl-2-propen-1-one(2E)-1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-oneVY06DZ94OCNSC-18939NSC-170284CHEBI:27916RVC-556DTXSID9061627RefChem:908433
이름 더 보기
(E)-2'-하이드록시칼콘NSC 170284(E)-2'-hydroxyone(E)-2'-Hydroxychalcontrans-2'-Hydroxychalcon2-Hydroxy-trans-chalcone2-(trans-Cinnamoyl)phenoltrans-2'-Hydroxycinnamophenone(E)-o-Hydroxyphenyl Styryl Ketone
DTXCID5033709212-962-0214-928-0888-12-01-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one(E)-2'-Hydroxychalconeo-HydroxychalconeChalcone, 2'-hydroxy-

데이터베이스 식별자

CAS
1214-47-7、888-12-0
PubChem CID
638276
DTXSID
DTXSID001313416
ChEMBL
CHEMBL32147
ChEBI
CHEBI:27916
UNII
VY06DZ94OC
EC Number
212-962-0、214-928-0、919-198-3
Nikkaji
J133.569C、J195.188B、J830.199I

물성

구조 계산 물성

XLogP
3.9
극성 표면적
37.3 Ų
수소 결합 공여자 수
1
수소 결합 수용자 수
2
회전 가능 결합 수
3
무거운 원자 수
17

실험 및 물리화학적 성질

Endocrine DisruptorsPotential endocrine disrupting compound

물리화학적 성질

녹는점
88 °C · 88 °C
저장 조건
Refrigerator
용해도
클로로포름, 에틸아세테이트, 메탄올에 용해됨
물리적 상태
고체
색상
노란색

화학적 성질

Yellow Solid

안전 및 규제

GHS 분류

GHS Classification · 5건

This chemical does not meet GHS hazard criteria for 2% (1 of 49) of reports.

Warning

H315 (89.8%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 49 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory InformationREACH registered substance: 2'-hydroxychalcone (EC: 214-928-0)
Hazard Classes and CategoriesSkin Irrit. 2 (89.8%)

안전 데이터

HS 번호
2914.50.3000

화학 및 산업

약리 정보

Metabolism/Metabolites2p-Hydroxychalcone has known human metabolites that include 2p-Hydroxychalcone, 2p-hydroxy-glucuronide.

용도 및 제조

General Manufacturing Information2-Propen-1-one, 1-(2-hydroxyphenyl)-3-phenyl-: ACTIVE

응용 분야

용도A synthetic chalcone with antibacterial and potential antitumoral activity.

상·하류 제품 정보

공급사32 곳

成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd+86-13119157289 · [email protected]
安徽合诺生物科技有限公司0555-2761852
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
欧利希（湖北）医药科技有限公司17316404525 17316404525 · [email protected]

추가 설명

정의ChEBI: A member of the class of chalcones that is trans-chalcone substituted by a hydroxy group at position 2'.

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