Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
다이뷰틸아미노에탄올
2-N-디부틸아미노에탄올 · N,N-디부틸에탄올아민 · 다이뷰틸아미노에탄올 · 다이부틸에탄올아민 · 2-(디부틸라미노)에탄올 · DBAE · DIBUTYLETHANOLAMINE · N,N-DIBUTYLETHANOLAMINE
식별자 및 물리적 특성
| CAS No. | 102-81-8 |
|---|---|
| 분자식 | C10H23NO |
| 평균 분자량 | 173.3 g/mol |
| 단동위원소 질량 | 173.17796436 g/mol |
| SMILES | CCCCN(CCO)CCCC |
| InChIKey | IWSZDQRGNFLMJS-UHFFFAOYSA-N |
| PubChem CID | 7621 |
| ChEMBL | CHEMBL1447214 |
| EC No. | 203-057-1 |
| DTXSID | DTXSID2024953 |
| 현지명 | 다이뷰틸아미노에탄올 |
화학 및 물리적 성질
| XLogP | 2.1 |
|---|---|
| 극성 표면적 | 23.5 |
| 수소 결합 공여자 수 | 1 |
| 수소 결합 수용자 수 | 2 |
| 회전 가능 결합 수 | 8 |
| 무거운 원자 수 | 12 |
| 형식 전하 | 0 |
| 복잡도 | 77.9 |
| 물질 분류 | Nitrogen Compounds -> EthanolaminesFlammable agents - 2nd degree |
| 밀도 | 0.85 (NTP, 1992) - Less dense than waterwill floatRelative density (water = 1): 0.90.860.86 g/mL at 25 °C(lit.) |
| 용해도 | less than 1 mg/mL at 64 °F (NTP, 1992)Solubility in water at 20 °C: poor0.4%Practically insoluble in water |
| 인화점 | 210 °F (NTP, 1992)90 °C c.c.195 °F197 °F |
| 끓는 점 | 435 to 450 °F at 760 mmHg (NTP, 1992)222-232 °C446 °F229-230 °C(lit.) |
| 녹는점 | -70 °C-70°C(lit.) |
| 증기 밀도 | 6 (NTP, 1992) - Heavier than airwill sink (Relative to Air)Relative vapor density (air = 1): 66 (vs air) |
| 증기압 | 0.1 mmHg (NIOSH, 2024)0.1 [mmHg]Vapor pressure, kPa at ? °C: 3.45Pa at 20℃ |
| Physical Description | Dibutylaminoethanol is a colorless liquid with a mild fishlike odor. Flash point 200 °F. Toxic by ingestion and skin absorption. Used to make other chemicals.Colorless liquid with a faint, amine-like odor[NIOSH]COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR.Colorless liquid with a faint, amine-like odor. |
| 자연 발화 온도 | 165 °C |
| 굴절률 | n20/D 1.444(lit.) |
| pKa(산도 계수) | 14.77±0.10(Predicted) |
| 물리적 상태 | 무색의 액체 |
| 색상 | Colorless to Light orange to Yellow |
| 용해도 | 4g/L at 20℃ |
| BRN | 1738441 |
| 안정성 | 안정적인. 타기 쉬운. 강한 산화제와 호환되지 않습니다. |
| 화장품 원료 기능 | 버퍼링 |
| InChI | 1S/C10H23NO/c1-3-5-7-11(9-10-12)8-6-4-2/h12H,3-10H2,1-2H3 |
| InChIKey | IWSZDQRGNFLMJS-UHFFFAOYSA-N |
| SMILES | CCCCN(CCO)CCCC |
| LogP(분배 계수) | 1.86 at 20℃ |
| EPA | 2-(Dibutylamino)ethanol (102-81-8) |
화학적 성질
colourless liquid
안전 및 규제
| GHS 분류 | DangerH302 (87.5%): Harmful if swallowed [Warning Acute toxicity, oral]P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P319, P321, P330, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 273 reports by companies from 13 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.H227: Combustible liquid [Warning Flammable liquids] |
|---|---|
| 규제 정보 | Chemical: Ethanol, 2-(dibutylamino)-Ethanol, 2-(dibutylamino)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Ethanol, 2-(dibutylamino)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 17-02-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/53362-N-Dibutylaminoethanol: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| 운송 라벨(DOT) | Poison |
| 화재 위험 | Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:· Combustible material: may burn but does not ignite readily.Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Above 90 °C explosive vapour/air mixtures may be formed. |
| 건강 유해성 | Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:· TOXIC and/or CORROSIVEinhalation, ingestion or skin contact with material may cause severe injury or death. |
| 유해성 요약 | In animals: irritation of eyes, skin, and nosecorneal necrosisweight loss[NIOSH] Molten substance may cause severe burns[CAMEO] May be corrosive to skin and eyes based on animal results[CHEMINFO] DBAE is an irritant of the nose and eyes. Animal studies show that DBAE inhibits acetylcholinesterase. The median lethal dose in rats dying of respiratory arrest is 89.1 mg/kg. Five rats with inhalation exposures of 33 ppm 6 hours a day for 5 days had no mortality. [ACGIH] |
| 운송 번호 및 가이드(DOT) | 2873 153 |
| 반응성 그룹 | Alcohols and Polyols |
| UN 분류 | UN Hazard Class: 6.1UN Pack Group: III |
| Reactivity Profile | DIBUTYLAMINOETHANOL is an aminoalcohol. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. |
| Chemical Dangers | Reacts with oxidants. Attacks many metals. This produces flammable/explosive gas (hydrogen - see ICSC 0001). Decomposes on burning. This produces nitrogen oxides. |
| Flammable Limits | Class IIIA Combustible Liquid: Fl.P. at or above 140 °F and below 200 °F. |
| Packaging and Labelling | Do not transport with food and feedstuffs. |
| 소화 | Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:Use water spray, alcohol-resistant foam, dry powder, carbon dioxide. |
| 응급 조치 | Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.Rinse mouth. Give one or two glasses of water to drink. Do NOT induce vomiting. Refer for medical attention . |
| 누출 비상 조치 | · CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. |
| 응급 처치 | EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.General First Aid:(General first aid procedures) |
| 안전 보관 | Separated from strong acids, oxidants, metals and food and feedstuffs. Well closed. Ventilation along the floor. |
| 노출 관리 및 개인 보호 | · Wear positive pressure self-contained breathing apparatus (SCBA). |
| 비화재 누출 대응 | Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: |
| 누출 처리 | Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Ventilation. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. |
| Isolation and Evacuation | Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:Immediate precautionary measure |
| Eye Prevention | Wear face shield. |
| Fire Prevention | NO open flames. NO contact with oxidizing agents. Above 90 °C use a closed system and ventilation. |
| Inhalation Risk | A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20 °C. |
| 표적 장기 | Eyes, skin, respiratory system |
| 유해 작용 | Dermatotoxin - Skin burns. |
| 노출 경로 | The substance can be absorbed into the body by inhalation, through the skin and by ingestion.inhalation, skin absorption, ingestion, skin and/or eye contact |
| Signs and Symptoms | Cough. Sore throat. Nausea. Convulsions. Dizziness. Laboured breathing. Pupillary constriction, muscle cramp, excessive salivation. Sweating. Unconsciousness.MAY BE ABSORBED! Skin burns. Pain. Redness. See Inhalation.Pain. Redness. Severe deep burns.Abdominal pain. Burning sensation. Shock or collapse. Abdominal cramps. Diarrhoea. Vomiting. See Inhalation.In Animals: irritation eyes, skin, nosedermatitisskin, corneal necrosisweight loss |
| ICSC Environmental Data | The substance is harmful to aquatic organisms. |
| 직업 노출 등급(OEB) | A |
| 직업 노출 한계(OEL) | TWA: 2 ppm (14 mg/m3) [skin] |
| 수질 위해 등급(WGK) | 1 |
| TSCA 등재 상태 | TSCA listed |
| RTECS 번호 | KK3850000 |
| 운송 번호(UN) | UN 2873 |
| 관세 코드 | 2922.19.9690 |
| 위험 문구(R) | 21/22-34 |
| 위험 표시 | C |
| 안전 문구(S) | 26-36/37/39-45 |
| 포장분류 | III |
| 위험 등급 | 6.1Acute Tox. 4 DermalAcute Tox. 4 OralAquatic Chronic 3Eye Dam. 1Skin Corr. 1CSTOT SE 3 |
| 기존화학 물질 | KE-09960 |
| 저장 분류 | 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects |
용도
용도
2-(Dibutylamino)ethanol (DBAE) may be used as a coreactant to enhance the electrochemiluminescence (ECL) of tris(2,2′-bipyridyl)ruthenium(II) [Ru(bpy)32+], employed in the ECL immunoassays and DNA probe assays. DBAE may also be used as a catalyst during the synthesis of protected D-erythro-(2S,3R)-sphingosine.
일반 설명
2-(DIBUTYLAMINO)ETHANOL is a colorless liquid with a mild fishlike odor. Flash point 200°F. Toxic by ingestion and skin absorption. Used to make other chemicals.