Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Dimethylamino-6-methoxyphenylboronic acid → N-(2,6-dichlorobenzoyl)-4-[2-(N,N-dimethylamino)-6-methoxyphenyl]-L-phenylalanine methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Dimethylamino-6-methoxyphenylboronic acid | HCID 4374258 | — |
| 반응물 | N-(2,6-dichlorobenzoyl)-4-bromo-L-phenylalanine methyl ester | HCID 54284267 | — |
| 생성물 | N-(2,6-dichlorobenzoyl)-4-[2-(N,N-dimethylamino)-6-methoxyphenyl]-L-phenylalanine methyl ester | HCID 54467033 | — |
반응 단계
2-Methoxy-6-(N,N-dimethylamino)benzene boronic acid was coupled with N-(2,6-dichlorobenzoyl)-4-bromo-L-phenylalanine methyl ester to give N-(2,6-dichlorobenzoyl)-4-[2-(N,N-dimethylamino)-6-methoxyphenyl]-L-phenylalanine methyl ester. The preparation of the boronic acid and the coupling reaction was carried out in a similar manner as described in Example 7.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06521666B1 |
| 출처 데이터셋 | uspto-grants-2003_02 |
| ORD ID | ord-a72ee172b4aa48b79b24397971122fce |
| 출처 메모 | uspto-grants-2003_02 |