Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(3-Bromophenyl)acrylic acid → 1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(3-bromophenyl)ethenyl)-1,3-diethyl-, (E)-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(3-Bromophenyl)acrylic acid | HCID 36251 | — |
| 반응물 | 5,6-Diamino-1,3-diethyluracil | HCID 4572133 | — |
| 생성물 | 1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(3-bromophenyl)ethenyl)-1,3-diethyl-, (E)- | HCID 6448930 | 51.1% |
반응 단계
Substantially the same procedure as in Reference Example 70 was repeated using 2.0 g (10.1 mmol) of 5,6-diamino-1,3-diethyluracil and 2.52 g (11.1 mmol) of 3-bromocinnamic acid. Then, the resultant crude crystals were recrystallized from tetrahydrofuran/water to give 2.01 g (yield 37%) of Compound 161 as pale green plates.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05543415 |
| 출처 데이터셋 | uspto-grants-1996_08 |
| ORD ID | ord-8fa31f38f45f41dbbfc33d97a4a47794 |
| 출처 메모 | uspto-grants-1996_08 |