Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Chloro-2,4-Dinitrobenzene → 4-Chloro-M-phenylenediamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Chloro-2,4-Dinitrobenzene | HCID 6 | — |
| 반응물 | HCID 86744256 | HCID 86744256 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Nickel | HCID 935 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 4-Chloro-M-phenylenediamine | HCID 21209 | — |
반응 단계
40.8 g of 1-chloro-2,4-dinitrobenzene, 2 g of Raney nickel (60%, aqueous), 2.3 g of N,N'-dibutylformamidine acetate and 120 ml of methanol are introduced in an autoclave equipped with gas introduction stirrer. The air in the autoclave is then displaced by nitrogen and then by hydrogen. The hydrogenation is carried out at a pressure of 10 bar and a temperature of 60° C. The hydrogenation time is 11/4 hours. 1-Chloro-2,4-diaminobenzene, 97% pure (analysed as 1-Chloro-2,4-acetamidobenzene by liquid chromatography), is obtained in quantitative yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04960936 |
| 출처 데이터셋 | uspto-grants-1990_10 |
| ORD ID | ord-45196dd3922c46828428291de1cdc84c |
| 출처 메모 | uspto-grants-1990_10 |