Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pyridine → 2-[2-Ethoxy-5-(4-methylpiperazin-1-yl-sulfonylamino)phenyl]-5-methyl-7-cyclopentyl-3H-imidazo-[5,1-f][1,2,4]-triazin-4-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | 4-methylpiperazine-1-sulfonyl Chloride | HCID 11171617 | — |
| 반응물 | 2-(5-Amino-2-ethoxyphenyl)-5-methyl-7-cyclopentyl-3H-imidazo[5,1-f][1,2,4]-triazin-4-one | HCID 135604941 | — |
| 생성물 | 2-[2-Ethoxy-5-(4-methylpiperazin-1-yl-sulfonylamino)phenyl]-5-methyl-7-cyclopentyl-3H-imidazo-[5,1-f][1,2,4]-triazin-4-one | HCID 135528493 | — |
반응 단계
120 mg (0.34 mmol) of the compound from example 42A are reacted with 319 mg (1.36 mmol) of 4-methyl-1-piperazinesulfonyl chloride in 8 ml (98.9 mmol) of pyridine overnight.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07098207B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-4248acda9a694d5a88d9c4ff651bf639 |
| 출처 메모 | uspto-grants-2006_08 |