Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pyridine → 2-[5-(Quinoline-8-sulfonamido)-2-propoxyphenyl]-5-methyl-7-cyclopentyl-3H-imidazo[5,1-f][1,2,4]-triazin-4-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | 8-Quinolinesulfonyl chloride | HCID 29220 | — |
| 반응물 | 2-(5-Amino-2-propoxyphenyl)-5-methyl-7-cyclopentyl-3H-imidazo[5,1-f][1,2,4]-triazin-4-one | HCID 135604925 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 2-[5-(Quinoline-8-sulfonamido)-2-propoxyphenyl]-5-methyl-7-cyclopentyl-3H-imidazo[5,1-f][1,2,4]-triazin-4-one | HCID 135604942 | — |
반응 단계
150 mg (0.408 mmol) of the compound from example 44A are reacted with 221 mg (0.96 mmol) of quinoline-8-sulfonyl chloride and 0.33 ml (4.08 mmol) of pyridine in 8 ml of tetrahydrofuran overnight.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07098207B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-83fb6179414c4b0e8890d174f5a96b0d |
| 출처 메모 | uspto-grants-2006_08 |