Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzenesulfonyl chloride → N-(3-Chloropropyl)-3,4-dimethoxy-N-methylphenethylamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzenesulfonyl chloride | HCID 7369 | — |
| 반응물 | 3-[N-methyl-N-(2-{3,4-dimethoxy-phenyl}-ethyl)amino]-propanol | HCID 15283521 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | N-(3-Chloropropyl)-3,4-dimethoxy-N-methylphenethylamine | HCID 577693 | — |
반응 단계
275 gm of benzenesulfonic acid chloride were added to 4 gm of 3-[N-methyl-N-(2-{3,4-dimethoxy-phenyl}-ethyl)amino]-propanol. After standing for 30 minutes, the mixture was dissolved in methylene chloride, washed with an aqueous 30% sodium hydroxide solution and water, dried over sodium sulfate and evaporated in vacuo. After purifying the residue on a silica gel column (eluant: methylene chloride/ethanol) a colorless oil was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04490369 |
| 출처 데이터셋 | uspto-grants-1984_12 |
| ORD ID | ord-ed8761a9700f43719d96aec357267180 |
| 출처 메모 | uspto-grants-1984_12 |