Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Methoxybenzoyl chloride → N-[3-(3-{2-[(3-fluorophenyl)amino]-4-pyrimidinyl}pyrazolo[1,5-a]pyridin-2-yl)phenyl]-2-(methyloxy)benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Methoxybenzoyl chloride | HCID 88969 | — |
| 반응물 | 4-[2-(3-aminophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-(3-fluorophenyl)-2-pyrimidinamine | HCID 59511403 | — |
| 반응물 | N-(3-{3-[2-(1,2,3,4-tetrahydro-7-isoquinolinylamino)-4-pyrimidinyl]-pyrazolo[1,5-a]pyridin-2-yl}phenyl)benzamide | HCID 59513880 | — |
| 생성물 | N-[3-(3-{2-[(3-fluorophenyl)amino]-4-pyrimidinyl}pyrazolo[1,5-a]pyridin-2-yl)phenyl]-2-(methyloxy)benzamide | HCID 59513869 | — |
반응 단계
In a manner analogous to Example 66, the title compound may be obtained by reacting 4-[2-(3-aminophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-(3-fluorophenyl)-2-pyrimidinamine and 2-methoxybenzoyl chloride. HRMS: calc. C28H20N6OFS calcd for C31H23FN6O2: 530.1867, found: 531.1941 (M+H)+ 507.1403 found 507.1427+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07812022B2 |
| 출처 데이터셋 | uspto-grants-2010_10 |
| ORD ID | ord-d45021e038d8439fac9324ccb590cf2e |
| 출처 메모 | uspto-grants-2010_10 |