Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → 3-Methylpyridine-4-carbonyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 3-Methyl-isonicotinic acid | HCID 1502003 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 3-Methylpyridine-4-carbonyl chloride | HCID 13285864 | — |
반응 단계
To 3-methylisonicotinic acid (100 mg, 0.729 mmol) suspended in DCM (2.5 mL) was added thionyl chloride (260 mg, 2.188 mmol). The reaction mixture was stirred at room temperature for about 3 hours. The solvent was removed under reduced pressure and the residue was dried under high vacuum for 1 hour to give 3-methyl-isonicotinoyl chloride.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07834039B2 |
| 출처 데이터셋 | uspto-grants-2010_11 |
| ORD ID | ord-1a1eef46b93945d4997458381914c3a8 |
| 출처 메모 | uspto-grants-2010_11 |