Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Chloro-4-fluorobenzoic acid → 3-chloro-4-fluoro-N-isopropylbenzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Chloro-4-fluorobenzoic acid | HCID 520989 | — |
| 반응물 | 2-Propanamine, hydrochloride (1:1) | HCID 6432137 | — |
| 생성물 | 3-chloro-4-fluoro-N-isopropylbenzamide | HCID 58324493 | — |
반응 단계
Using isopropylamine hydrochloride and 3-chloro-4-fluorobenzoic acid in the general procedure for coupling of amines to carboxylic acids, the title compound was obtained as a white solid (81% yield). ESI-MS: m/z 216 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08669249B2 |
| 출처 데이터셋 | uspto-grants-2014_03 |
| ORD ID | ord-b6623b9069534d28a5ebf78d10498bef |
| 출처 메모 | uspto-grants-2014_03 |