Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N,N-Dimethylaniline → 6-Chloro-2[[4-(dimethylamino)phenyl]amino]3-nitrobenzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N,N-Dimethylaniline | HCID 949 | — |
| 반응물 | N,N-dimethyl-p-phenylenediamine | HCID 7472 | — |
| 반응물 | 2,6-Dichloro-3-nitrobenzoic acid | HCID 350623 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 6-Chloro-2[[4-(dimethylamino)phenyl]amino]3-nitrobenzoic acid | HCID 13588348 | — |
반응 단계
A mixture of 41.0 g of N,N-dimethyl-p-phenylenediamine, 100 ml of N,N-dimethylaniline, and 23.6 g of 2,6-dichloro-3-nitrobenzoic acid was heated for seven hours on a steam bath. The resulting cake was suspended in dichloromethane, filtered, and the solid washed with water. Recrystallization from DMF-ethanol provided 6-chloro-2[[4-(dimethylamino)phenyl]amino]-3-nitrobenzoic acid, mp 222°-223° C. (dec).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04626540 |
| 출처 데이터셋 | uspto-grants-1986_12 |
| ORD ID | ord-be0cc871550e43d7b1fe5ba975f8ad50 |
| 출처 메모 | uspto-grants-1986_12 |