Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzaldehyde → Ethyl 2-(benzylideneamino)acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzaldehyde | HCID 240 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Sulfuric acid magnesium salt (1:1) | HCID 24083 | — |
| 반응물 | Glycine ethyl ester, hydrochloride | HCID 2723640 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | Ethyl 2-(benzylideneamino)acetate | HCID 357745 | — |
반응 단계
To ethyl glycinate hydrochloride (36.4 g) suspended in 500 ml methylene chloride were added magnesium sulfate (22 g) and triethylamine (72 ml, 52.4 g). Benzaldehyde (27.6 g) was added dropwise at 15°-20° C. with stirring. The mixture was stirred at room temperature for two hours, filtered and stripped. To the residue was added 300 ml diethylether and 150 ml brine. After separation the organic layer was collected, and the aqueous layer was extracted with 100 ml ether. The organic phases were combined, dried (MgSO4), filtered and stripped to yield the title product as a pale yellow oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04456467 |
| 출처 데이터셋 | uspto-grants-1984_06 |
| ORD ID | ord-aa81e46f05784623b13d2ebc3b0c126b |
| 출처 메모 | uspto-grants-1984_06 |