Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Bromomethyl-2-furancarboxylic acid ethyl ester → 5-[[5-{2,8-Dichloro-5H-dibenzo[a,d]cyclohepten-5-yl}-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-2-furancarboxylic acid, ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Bromomethyl-2-furancarboxylic acid ethyl ester | HCID 13789529 | — |
| 반응물 | 5-[2,8-Dichloro-5H-dibenzo[a,d]cyclohepten-5-yl]-2,4(1H,3H)-pyrimidinedione | HCID 22117251 | — |
| 생성물 | 5-[[5-{2,8-Dichloro-5H-dibenzo[a,d]cyclohepten-5-yl}-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-2-furancarboxylic acid, ethyl ester | HCID 86756130 | — |
반응 단계
The subtitle compound was prepared from the product of step (vi) (0.54 g) and 5-bromomethyl-2-furancarboxylic acid ethyl ester (J. Chem. Soc. Perkin Trans. 1, 1981, 1125, Bull. Chem. Soc. Jpn. 1987, 60, 1807)(0.34 g) according to the method of example 1 step (iv). Purification was by chromatography eluting with 30% ethyl acetate in isohexane. Yield 0.55 g.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06162808 |
| 출처 데이터셋 | uspto-grants-2000_12 |
| ORD ID | ord-3fd3a66ae35b499eac98efc94d7e60f7 |
| 출처 메모 | uspto-grants-2000_12 |