Chloromethyl Methyl Ether → HCID 20285666, 화합물

HRID 127737

반응식

HRID 127737 반응식
[CH3:1][C:2]1[S:3][C:4]([CH3:8])=[CH:5][C:6]=1[CH3:7].CO[CH2:11][Cl:12]>C(O)(=O)C>[CH3:8][C:4]1[S:3][C:2]([CH3:1])=[C:6]([CH3:7])[C:5]=1[CH2:11][Cl:12]

참가 물질

4

반응물 2

HCID 7864Chloromethyl Methyl EtherHCID 745312,3,5-Trimethylthiophene

생성물 1

HCID 20285666HCID 20285666, 화합물

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

24.6 G. of 2,3,5-trimethyl-thiophene, 14.8 g. of freshly distilled chloromethyl methyl ether and 52 g. of glacial acetic acid were combined in a glass pressure bottle and stirred at room temperature for 41/2 hours. The resulting reaction mixture was poured into ice water, stirred for 10 min. and extracted with benzene. The combined benzene extracts were washed twice with saturated sodium chloride solution, dried over sodium sulfate, filtered and evaporated. The resulting 2,4,5-trimethyl-3-chloromethyl-thiophene was used for the next step without any further purification.

후처리

  1. customThe resulting reaction mixture
  2. stirringstirred for 10 min.
  3. extractionextracted with benzene
  4. washThe combined benzene extracts were washed twice with saturated sodium chloride solution
  5. dry with materialdried over sodium sulfate
  6. filtrationfiltered
  7. customevaporated
  8. customThe resulting 2,4,5-trimethyl-3-chloromethyl-thiophene was used for the next step without any further purification

출처 및 근거

ORD 기록
ord-17520cada3214c5b85206ea84d95e33a
출처 데이터셋
uspto-grants-1981_03
특허 번호
US04256878

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