Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Chloro-2-methylphenyl isothiocyanate → 1-(5-Chloro-2-methyl-phenyl)-3-(2-methyl-benzothiazol-5-yl)-thiourea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Chloro-2-methylphenyl isothiocyanate | HCID 29519 | — |
| 반응물 | 5-Benzothiazolamine, 2-methyl- | HCID 36229 | — |
| 생성물 | 1-(5-Chloro-2-methyl-phenyl)-3-(2-methyl-benzothiazol-5-yl)-thiourea | HCID 10291386 | 29.3% |
반응 단계
Prepared using Method A from 4.5 g (24.5 mmol) of 5-chloro-2-methyl-phenyl isothiocyanate and 4.02 g (24.5 mmol) of 5-amino-2-methylbenzothiazole to give 6.0 g of crude material. Soxhlet extraction with EtOAc gave 2.5 g of pure title compound as a tan solid (29% yield, m.p. 173-174° C. ).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06455566B1 |
| 출처 데이터셋 | uspto-grants-2002_09 |
| ORD ID | ord-17ece07f429645d68db02adf78e1502e |
| 출처 메모 | uspto-grants-2002_09 |