Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → Methyl 2-methyl-3-nitrobenzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | 2-Methyl-3-nitrobenzoic acid | HCID 16096 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 생성물 | Methyl 2-methyl-3-nitrobenzoate | HCID 601165 | — |
반응 단계
To 2-methyl-3-nitrobenzoic acid (10.0 g) is added methanol (100 ml) and thereto thionyl chloride (8 ml) is added dropwise at room temperature. After reflux for 2 hours, the reaction mixture is poured into ice-water and extracted with dichloromethane. The solvent is concentrated to give methyl 2-methyl-3-nitrobenzoate (10.8 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05723648 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-c6d1437bef5145cca37826ac5ae090f0 |
| 출처 메모 | uspto-grants-1998_03 |