Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethyl Sulfate → HCID 15125726, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethyl Sulfate | HCID 6497 | — |
| 반응물 | Methyl formate | HCID 7865 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 3-Phenoxyphenol | HCID 12842 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 2-Bromobenzaldehyde | HCID 81129 | — |
| 반응물 | HCID 10861730 | HCID 10861730 | — |
| 반응물 | Methyl 2-(3-methoxyphenoxy)benzeneacetate | HCID 14620154 | — |
| 반응물 | (E)-methyl 2-[2-(3-hydroxyphenoxy)phenyl]-3-methoxypropenoate | HCID 14620157 | — |
| 생성물 | HCID 15125726 | HCID 15125726 | — |
반응 단계
Methyl 2-(3-phenoxyphenoxy)phenylacetate was prepared from 3-phenoxyphenol and 2-bromobenzaldehyde by the steps described in Example 1 for the preparation of methyl 2-(3-methoxyphenoxy)phenylacetate. This was the converted into (E)-methyl 3-methoxy-2-[2-(3-phenoxyphenoxy) phenyl]propenoate [1H n.m.r (250 MHz) 3.61 (3H, s), 3.78 (3H, s), 6.68-7.35 (13H, m), 7.48 (1H, s) ppm] using sodium hydride and methyl formate, and then potassium carbonate and dimethyl sulphate, using the procedure described in Example 1 for the preparation of (E)-methyl 2-[2-(3-hydroxyphenoxy)phenyl]-3-methoxypropenoate, except that just 2 equivalents of sodium hydride were used in this case.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05468857 |
| 출처 데이터셋 | uspto-grants-1995_11 |
| ORD ID | ord-5570be487ca14746a87360442f67b0ac |
| 출처 메모 | uspto-grants-1995_11 |