Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrazine hydrate (1:1) → 1-(3-Aminopropyl)-4-diphenylmethylpiperidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 반응물 | 4-Diphenylmethyl-1-(3-phthalimidopropyl)piperidine | HCID 19370298 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 1-(3-Aminopropyl)-4-diphenylmethylpiperidine | HCID 23004117 | 47.2% |
반응 단계
A mixture of 2.8 g of 4-diphenylmethyl-1-(3-phthalimidopropyl)piperidine (prepared as described in Preparation 44') and 0.90 g of hydrazine hydrate in 100 ml of ethanol was heated under reflux for 2 hours. At the end of this time, the mixture was cooled to room temperature and filtered. The mixture was concentrated by evaporation under reduced pressure, to give 0.93 g (yield 47%) of the title compound as an oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05470851 |
| 출처 데이터셋 | uspto-grants-1995_11 |
| ORD ID | ord-e324caf083124e8aa7c77ccd632fc52c |
| 출처 메모 | uspto-grants-1995_11 |