5-(2-Fluoropyridin-3-yloxy)-6-(6-ethanesulfonyl-pyridin-3-yloxy)-2-pyridin-2-yl-1H-benzimidazole → HCID 178477650, 화합물

HRID 13318

반응식

HRID 13318 반응식
[F:1][C:2]1[C:7]([O:8][C:9]2[C:23]([O:24][C:25]3[CH:26]=[N:27][C:28]([S:31]([CH2:34][CH3:35])(=[O:33])=[O:32])=[CH:29][CH:30]=3)=[CH:22][C:12]3[NH:13][C:14]([C:16]4[CH:21]=[CH:20]C=C[N:17]=4)=[N:15][C:11]=3[CH:10]=2)=[CH:6][CH:5]=[CH:4][N:3]=1.[NH:36]1C=CC(C=O)=N1>>[F:1][C:2]1[C:7]([O:8][C:9]2[C:23]([O:24][C:25]3[CH:26]=[N:27][C:28]([S:31]([CH2:34][CH3:35])(=[O:32])=[O:33])=[CH:29][CH:30]=3)=[CH:22][C:12]3[NH:13][C:14]([C:16]4[CH:21]=[CH:20][NH:36][N:17]=4)=[N:15][C:11]=3[CH:10]=2)=[CH:6][CH:5]=[CH:4][N:3]=1

참가 물질

3

반응물 2

HCID 113523445-(2-Fluoropyridin-3-yloxy)-6-(6-ethanesulfonyl-pyridin-3-yloxy)-2-pyridin-2-yl-1H-benzimidazoleHCID 122183831H-Pyrazole-3-carbaldehyde

생성물 1

HCID 178477650HCID 178477650, 화합물

실험 절차

The entitled compound was obtained as a colorless solid in the same method as in Example 202 or in accordance with the method or by combining it with an ordinary method but using 4-(2-fluoropyridin-3-yloxy)-5-(6-ethanesulfonyl-pyridin-3-yloxy)-benzene-1,2-diamine obtained in Example 239, and 1H-pyrazole-3-carboxaldehyde.

후처리

  1. customThe entitled compound was obtained as a colorless solid in the same method as in Example 202 or in accordance with the method

출처 및 근거

ORD 기록
ord-00d3805c855b4c5eac37eeb3a680c548
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07728025B2

연결된 노트

불러오는 중…