참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Methyl 3-(methyl(pentyl)amino)propanoate | HCID 16726422 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 3-(N-Methylpentylamino)propionic acid hydrochloride | HCID 16726423 | 82.7% |
반응 단계
68.8 g (367.4 mmol) N-methyl-N-pentyl-β-alanine methyl ester was hydrolyzed by refluxing with 138 ml water. Then the water is partly distilled off and 83 ml (472.7 mmol) hydrochloric acid (19%) was added. Water was distilled off again and 230 ml methyl ethyl ketone was added to remove residual water by azeotropic distillation. The reaction mixture was then cooled to 24° C. The crystallized product was separated and washed with methyl ethyl ketone and subsequently dried in vacuo. 63.7 g (82.7%) N-methyl-N-pentyl-β-alanine hydrochloride were obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07214818B2 |
|---|
| 출처 데이터셋 | uspto-grants-2007_05 |
|---|
| ORD ID | ord-744adb86bb3e4a93923a6ff91260a4e5 |
|---|
| 출처 메모 | uspto-grants-2007_05 |
|---|
