참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 1-Phenylisatin | HCID 12884 | — |
| 반응물 | 5-Benzothiazolamine, 2-methyl- | HCID 36229 | — |
| 생성물 | 3-[(2-Methyl-1,3-benzothiazol-5-YL)imino]-1-phenyl-1,3-dihydro-2H-indol-2-one | HCID 9999162 | 32.3% |
반응 단계
5-amino-2-methylbenzothiazole (52.2 mg, 0.31 mmol) was mixed with 1-phenylisatin (69.7 mg, 0.31 mmol) and heated at 140° C. for 3 h. The resulting crude product was purified by preparative TLC using ethyl acetate/hexane (6:4) as the eluent to give the desired product as a yellow solid (36.9 ma, 32.3%). 1H NMR Data: δ 7.9-6.7 (m, 12H), 2.9 (s, 3H). ESI-MS m/z found 370 (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07220775B2 |
|---|
| 출처 데이터셋 | uspto-grants-2007_05 |
|---|
| ORD ID | ord-9a760ef07ca54aeea9dcbd24671eb613 |
|---|
| 출처 메모 | uspto-grants-2007_05 |
|---|
