Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl indole-2-carboxylate → 5-fluoro-1-methyl-1H-indole-3-carbaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl indole-2-carboxylate | HCID 73125 | — |
| 반응물 | 5-fluoro-1H-indole-3-carbaldehyde | HCID 259089 | — |
| 생성물 | 5-fluoro-1-methyl-1H-indole-3-carbaldehyde | HCID 1382009 | 50% |
반응 단계
According to the procedure of Preparation 9 (a), except substituting 5-fluoro-1H-indole-3-carboxaldehyde (0.3 g, 1.8 mmole) for the ethyl indole-2-carboxylate, the title compound (0.16 g, 50%) was prepared as a viscous oil: MS (ES) m/e 178 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07879872B2 |
| 출처 데이터셋 | uspto-grants-2011_02 |
| ORD ID | ord-bdd95ea46f684e56b350d52250163e65 |
| 출처 메모 | uspto-grants-2011_02 |