Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → 5-Bromonicotinoyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 5-Bromonicotinic acid | HCID 88707 | — |
| 생성물 | 5-Bromonicotinoyl chloride | HCID 2781223 | — |
반응 단계
To 5.00 g of 5-bromonicotinic acid, 74 ml of thionyl chloride was added and the mixture was heated at reflux for 6 hours. After the solvent was distilled off under reduced pressure, the crystal was washed with diisopropyl ether and collected by filtration to obtain 4.09 g of the objective compound as colorless crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07728131B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-13b18ee5ae764080a25434c0db579b45 |
| 출처 메모 | uspto-grants-2010_06 |