2-(1-Piperazinyl)-4-amino-6,7-dimethoxyquinazoline → HCID 21183937, 화합물

HRID 1384945

반응식

HRID 1384945 반응식
[S:1]1[CH:5]=[C:4]([C:6]([Cl:8])=[O:7])[N:3]=[CH:2]1.[NH2:9][C:10]1[C:19]2[C:14](=[CH:15][C:16]([O:22][CH3:23])=[C:17]([O:20][CH3:21])[CH:18]=2)[N:13]=[C:12]([N:24]2[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]2)[N:11]=1>>[ClH:8].[NH2:9][C:10]1[C:19]2[C:14](=[CH:15][C:16]([O:22][CH3:23])=[C:17]([O:20][CH3:21])[CH:18]=2)[N:13]=[C:12]([N:24]2[CH2:29][CH2:28][N:27]([C:6]([C:4]3[N:3]=[CH:2][S:1][CH:5]=3)=[O:7])[CH2:26][CH2:25]2)[N:11]=1

참가 물질

3

반응물 2

HCID 6162672-(1-Piperazinyl)-4-amino-6,7-dimethoxyquinazolineHCID 155721001,3-Thiazole-4-carbonyl chloride

생성물 1

HCID 21183937HCID 21183937, 화합물

실험 절차

The title compound was prepared from thiazole-4-carbonyl chloride (1.02 g.) and 4-amino-6,7-dimethoxy-2-(1-piperazinyl)quinazoline (2.00 g.) following previously described procedures. The product had a m.p. of 274°-277° C. with decomposition.

출처 및 근거

ORD 기록
ord-8e938068c6f249b0876d7191ca4d4a7d
출처 데이터셋
uspto-grants-2001_07
특허 번호
US06262059B1

연결된 노트

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