Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(Chlorosulfonyl)benzoic acid → 4-(N-methyl-N-(4-(trifluoromethyl)phenyl)sulfamoyl)benzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(Chlorosulfonyl)benzoic acid | HCID 82385 | — |
| 반응물 | N-Methyl-4-(trifluoromethyl)aniline | HCID 15099755 | — |
| 생성물 | 4-(N-methyl-N-(4-(trifluoromethyl)phenyl)sulfamoyl)benzoic acid | HCID 66762384 | — |
반응 단계
4-(chlorosulfonyl)benzoic acid (0.5 g, 2.27 mmol) was treated with N-methyl-4-(trifluoromethyl)aniline (1191 mg, 6.80 mmol) using method A to give 4-(N-methyl-N-(4-(trifluoromethyl)phenyl)sulfamoyl)benzoic acid as a white solid. Yield: 385 mg (47%). 1H-NMR: 8.11 (d, J=8.5 Hz, 2H), 7.74 (d, J=8.5 Hz, 2H), 7.66 (d, J=8.5 Hz, 2H), 7.39 (d, J=8.5 Hz, 2H), 3.21 (s, 3H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08901306B2 |
| 출처 데이터셋 | uspto-grants-2014_12 |
| ORD ID | ord-0bddc6ccedcb4a7eafaddc35e265fde2 |
| 출처 메모 | uspto-grants-2014_12 |