Ethanolamine → HCID 21408176, 화합물

HRID 1414860

반응식

HRID 1414860 반응식
[C:1]([C:4]1[CH:9]=[N+:8]([O-:10])[C:7]([CH3:11])=[CH:6][N:5]=1)([OH:3])=[O:2].C(CN)O>CO>[CH2:1]([CH2:4][NH2:5])[OH:2].[C:1]([C:4]1[CH:9]=[N+:8]([O-:10])[C:7]([CH3:11])=[CH:6][N:5]=1)([OH:3])=[O:2]

참가 물질

4

반응물 2

HCID 700EthanolamineHCID 5310993Acipimox

생성물 1

HCID 21408176HCID 21408176, 화합물수율 120.3%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

2-Carboxy-5-methylpyrazine 4-oxide (2.5 g) was added to methanol (60 ml) and ethanolamine (1.1 ml). The mixture was refluxed for 20 minutes, then cooled and filtered to obtain 2-carboxy-5-methylpyrazine 4-oxide ethanolamine salt (2.1 g), m.p. 177°-180° C, after crystallisation from methanol.

후처리

  1. temperatureThe mixture was refluxed for 20 minutes
  2. temperaturecooled
  3. filtrationfiltered

출처 및 근거

ORD 기록
ord-69e379b6fcd04fc388045f6b6382e596
출처 데이터셋
uspto-grants-1977_01
특허 번호
US04002750

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