Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl quinoline-7-carboxylate → Methyl 1,2,3,4-tetrahydroquinoline-7-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl quinoline-7-carboxylate | HCID 12554532 | — |
| 촉매 | Adams' catalyst | HCID 345198 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | Methyl 1,2,3,4-tetrahydroquinoline-7-carboxylate | HCID 16244389 | 98.8% |
반응 단계
A solution of methyl quinoline-7-carboxylate (185 mg, 1.0 mmol) and PtO2 (20 mg) in methanol (10 mL) was shaken under an atmosphere of hydrogen for 2 h. The reaction mixture was filtered through diatomaceous earth, and concentrated under reduced pressure to provide methyl 1,2,3,4-tetrahydroquinoline-7-carboxylate (189 mg): ESI MS m/z 192 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07727997B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-b463b69e32e84ebcae43fe823eba9ec4 |
| 출처 메모 | uspto-grants-2010_06 |