Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Chloro-6,7,8-trimethoxyquinazoline → HCID 22923429, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Chloro-6,7,8-trimethoxyquinazoline | HCID 100686 | — |
| 반응물 | 1,2,3,4-Tetrahydro-1,6-dimethyl-2,4-dioxo-3-(4-piperidinyl)quinazoline hydrobromide | HCID 21851222 | — |
| 생성물 | HCID 22923429 | HCID 22923429 | 25% |
반응 단계
The procedure similar to that described in Example 57 was repeated, except that 1.06 g (3.0 mmol) of 1,2,3,4-tetrahydro-1,6-dimethyl-2,4-dioxo-3-(4-piperidinyl)quinazoline hydrobromide (Compound v) obtained in Example 41 was used and 4-chloro-6,7,8-trimethoxyquinazoline was used in place of 4-chloro-6,7-dimethoxyquinazoline. As a result, 365.1 mg (yield: 25%) of Compound 86 was obtained as white crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05605900 |
| 출처 데이터셋 | uspto-grants-1997_02 |
| ORD ID | ord-1c08b2c553af49e19c1eefe528f3a07c |
| 출처 메모 | uspto-grants-1997_02 |