Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1H-Indazol-5-amine → 2-methylsulfonyl-N-(1H-indazol-5-yl)benzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1H-Indazol-5-amine | HCID 88012 | — |
| 반응물 | 2-Methanesulfonylbenzene-1-sulfonyl chloride | HCID 2735178 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | 2-methylsulfonyl-N-(1H-indazol-5-yl)benzenesulfonamide | HCID 11725502 | 24.3% |
반응 단계
2-Methylsulfonyl-N-(1H-indazol-5-yl)benzenesulfonamide can be obtained as described in Example 2 from 1 g of 5-amino-1H-indazole, 20 ml of pyridine and 1.91 g of 2-methylsulfonylbenzenesulfonyl chloride. 0.64 g of 2-methylsulfonyl-N-(1H-indazol-5-yl)benzenesulfonamide is thus obtained in the form of a white solid melting at 245° C. (analysis C14H13N3O4S2 % calculated C, 47.85; H, 3.73; N, 11.96; O, 18.21; S, 18.25. % found C, 47.42; H, 3.72; N, 11.64; S, 17.97).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07473701B2 |
| 출처 데이터셋 | uspto-grants-2009_01 |
| ORD ID | ord-fcbec3c8bbc34b579e123a8a1e8ca958 |
| 출처 메모 | uspto-grants-2009_01 |