Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzylideneacetone → 3-(Aminomethyl)-6-methyl-4-phenyl-2(1H)-pyridinone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzylideneacetone | HCID 637759 | — |
| 반응물 | 3-(Aminomethyl)-6-methyl-4-propylpyridin-2(1H)-oneacetate | HCID 67124140 | — |
| 생성물 | 3-(Aminomethyl)-6-methyl-4-phenyl-2(1H)-pyridinone | HCID 67124292 | — |
반응 단계
The title compound was prepared in the same manner as described for 3-(aminomethyl)-6-methyl-4-propyl-2(1H)-pyridinone (Intermediate 5) using (3E)-4-phenyl-3-buten-2-one (20 g, 137 mmol). LCMS E-S(M+H)=215.0. 1H NMR (400 MHz, DMSO-d6) δ ppm 12.2-12.3 (br s, 1H), 7.88-8.00 (br s, 3H), 7.43-7.51 (m, 3H), 7.29-7.38 (m, 2H), 6.08 (s, 1H), 3.67-3.70 (m, 2H), 2.23 (s, 3H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09402836B2 |
| 출처 데이터셋 | uspto-grants-2016_08 |
| ORD ID | ord-5cda6ca7ed584376b7dd0043f74476ec |
| 출처 메모 | uspto-grants-2016_08 |