Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Z-Hyp(Tbu)-OH → (2S,4S)-4-amino-2-(5-phenyl-oxazol-2-yl)-pyrrolidine-1-carboxylic acid benzyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Z-Hyp(Tbu)-OH | HCID 6950951 | — |
| 반응물 | (2S,4S)-4-Amino-2-oxazol-2-yl-pyrrolidine-1-carboxylic acid benzyl ester | HCID 89768242 | — |
| 생성물 | (2S,4S)-4-amino-2-(5-phenyl-oxazol-2-yl)-pyrrolidine-1-carboxylic acid benzyl ester | HCID 89768393 | — |
반응 단계
(2S,4S)-4-amino-2-(5-phenyl-oxazol-2-yl)-pyrrolidine-1-carboxylic acid benzyl ester was prepared from (2S,4R)-4-tert-butoxy-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester in a similar reaction sequence used in the preparation of (2S,4S)-4-amino-2-oxazol-2-yl-pyrrolidine-1-carboxylic acid benzyl ester. MS calcd. for C21H22N3O3 [(M+H)+] 364, obsd. 364.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09403805B2 |
| 출처 데이터셋 | uspto-grants-2016_08 |
| ORD ID | ord-ee40495a29e64e9fa21b624d0868538e |
| 출처 메모 | uspto-grants-2016_08 |