Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(2R)-2-Amino-3,3-dimethylbutan-1-ol → 5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid ((R)-1-hydroxymethyl-2,2-dimethyl-propyl)-amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (2R)-2-Amino-3,3-dimethylbutan-1-ol | HCID 6932847 | — |
| 반응물 | 5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid | HCID 90203638 | — |
| 생성물 | 5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid ((R)-1-hydroxymethyl-2,2-dimethyl-propyl)-amide | HCID 76283444 | — |
반응 단계
The title compound was synthesized in analogy to Example 1, using 5-chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid and (2R)-2-amino-3,3-dimethyl-1-butanol (CAN 112245-09-7) as starting materials and isolated (80 mg, 80%) as colorless oil; LC-MS (UV peak area, m/z) 100%, 327.1476 (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09409866B2 |
| 출처 데이터셋 | uspto-grants-2016_08 |
| ORD ID | ord-00014752e5cd4091b6963e4de7d701a2 |
| 출처 메모 | uspto-grants-2016_08 |