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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 14825생성일: 2026년 10월 24일

Methanesulfonyl chloride → 3-{[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-methanesulfonyl-amino}-pyrrolidine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/ko/reaction/14825

반응식

참여 물질

역할이름HCID투입량
반응물Methanesulfonyl chlorideHCID 31297—
반응물3-[3-(2-Chloro-pyrimidin-4-yl)-benzylamino]-pyrrolidine-1-carboxylic acid tert-butyl esterHCID 86603268—
생성물3-{[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-methanesulfonyl-amino}-pyrrolidine-1-carboxylic acid tert-butyl esterHCID 86603269—

반응 단계

Intermediate 53 was coupled with methanesulfonyl chloride following procedure D. LC-MS showed the product had the expected M+H+ of 467.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07732444B2
출처 데이터셋uspto-grants-2010_06
ORD IDord-2e567960199b4a0e935792987e7f330e
출처 메모uspto-grants-2010_06