Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
tert-Butyl 3-(aminomethyl)pyrrolidine-1-carboxylate → 3-{[3-(2-Chloro-pyrimidin-4-yl)-benzylamino]-methyl}-pyrrolidine-1-carboxylic acid tert-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | tert-Butyl 3-(aminomethyl)pyrrolidine-1-carboxylate | HCID 2756485 | — |
| 반응물 | 3-(2-Chloro-pyrimidin-4-yl)-benzaldehyde | HCID 24901965 | — |
| 생성물 | 3-{[3-(2-Chloro-pyrimidin-4-yl)-benzylamino]-methyl}-pyrrolidine-1-carboxylic acid tert-butyl ester | HCID 86603279 | — |
반응 단계
Intermediate 1 was coupled with 3-Aminomethyl-pyrrolidine-1-carboxylic acid tert-butyl ester following procedure B. LC-MS showed the product had the expected M+H+ of 403.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07732444B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-90a6330773f14fc6afd87a1a5c12a5a6 |
| 출처 메모 | uspto-grants-2010_06 |