Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl Thioglycolate → 6-Bromo-benzo[b]thiophene-2-carboxylic acid methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl Thioglycolate | HCID 16907 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 4-Bromo-2-fluorobenzaldehyde | HCID 143517 | — |
| 생성물 | 6-Bromo-benzo[b]thiophene-2-carboxylic acid methyl ester | HCID 22474078 | — |
반응 단계
Using 6.54 g (32.2 mmol) of 4-bromo-2-fluorobenzaldehyde, 1.93 g (48.3 mmol) of sodium hydride (60% pure) and 3.76 g (35.5 mmol) of methyl mercaptoacetate, 4.06 g (46.4% of theory) of the title compound are obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07732477B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-02697ddfe95a41e5a370efea5aeb175c |
| 출처 메모 | uspto-grants-2010_06 |