Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrogen Cyanide → 4-Hydroxy-3-methoxyphenylacetonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrogen Cyanide | HCID 768 | — |
| 반응물 | Vanillyl alcohol | HCID 62348 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | 4-Hydroxy-3-methoxyphenylacetonitrile | HCID 78220 | — |
반응 단계
185g of 3-methoxy-4-hydroxybenzyl alcohol are dissolved in 1,250 ml of DMSO and 35g of anhydrous hydrocyanic acid are passed in over the course of 1 hour at 125°C. The mixture is then stirred for a further 2 hours, and worked up as indicated above. The yield was 160.5g (82% of theory).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03983160 |
| 출처 데이터셋 | uspto-grants-1976_09 |
| ORD ID | ord-70f38d4a54f142658a425b4605e80135 |
| 출처 메모 | uspto-grants-1976_09 |