Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trimethylacetamide → N-(4-Fluoro-3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2,2-dimethylpropanamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trimethylacetamide | HCID 12957 | — |
| 반응물 | 5-{4-[2-(5-Bromo-2-fluorophenyl)ethyl]-1-piperazinyl}-2-methylquinoline | HCID 57444350 | — |
| 생성물 | N-(4-Fluoro-3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2,2-dimethylpropanamide | HCID 57444352 | 52% |
반응 단계
The title compound was prepared in 52% yield according to the general procedure for the preparation of amides, ureas and carbamates (Method A) starting from 5-{4-[2-(5-bromo-2-fluorophenyl)ethyl]-1-piperazinyl}-2-methylquinoline and 2,2-dimethylpropanamide.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07732600B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-c28b54965a6b4f309b805380e3a65a6d |
| 출처 메모 | uspto-grants-2010_06 |